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Colorado ( , other variants) is a state in the Mountain West sub-region of the Western United States. It encompasses most of the Southern Rocky Mountains, as well as the northeastern portion of the Colorado Plateau and the western edge of the Great Plains. Colorado is the eighth most extensive and 21st most populous U.S. state. The United States Census Bureau estimated the population of Colorado at 5,839,926 as of July 1, 2022, a 1.15% increase since the 2020 United States census.The region has been inhabited by Native Americans and their ancestors for at least 13,500 years and possibly much longer. The eastern edge of the Rocky Mountains was a major migration route for early peoples who spread throughout the Americas.